Roles of adapalene in the treatment of pityriasis versicolor.
Dermatology
; 224(2): 184-8, 2012.
Article
em En
| MEDLINE
| ID: mdl-22572567
ABSTRACT
BACKGROUND:
Ketoconazole is a typical treatment available for pityriasis versicolor; tretinoin cream is effective, too. Adapalene gel is a tretinoin derivative and has a lower incidence of irritation compared with other topical retinoid products. However, there are no reports on adapalene gel for the treatment of pityriasis versicolor.OBJECTIVE:
To study the effect of adapalene gel comparing the treatment with adapalene gel and 2% ketoconazole cream in pityriasis versicolor.METHODS:
Eighty patients suffering from pityriasis versicolor were randomly divided into two groups; one group were treated with 2% ketoconazole cream topically twice daily for 2 weeks, adapalene gel was used for the other group in a similar fashion.RESULTS:
There were no significant differences in efficacy between the two groups. No major side effects were noted in any of the groups either.CONCLUSION:
Adapalene was the favorable option in the treatment of pityriasis versicolor. The probable therapeutic mechanism of adapalene is also discussed.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Tinha Versicolor
/
Fármacos Dermatológicos
/
Cetoconazol
/
Naftalenos
Tipo de estudo:
Clinical_trials
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article