Infants weighing <1500 g: better born too small or too soon?
Am J Perinatol
; 29(9): 693-8, 2012 Oct.
Article
em En
| MEDLINE
| ID: mdl-22644828
ABSTRACT
OBJECTIVE:
To evaluate the influence of intrauterine growth on intact neurological outcome at 12 to 24 months in a cohort of infants weighing <1500 g at birth. STUDYDESIGN:
This retrospective study was conducted in the Department of Obstetrics and Gynecology, University of Milano-Bicocca, San Gerardo Hospital, Monza, Italy. Perinatal variables were correlated with occurrence of composite adverse outcome, including neonatal death or adverse neurodevelopmental outcome (ANDO), at 12 to 24 months' follow-up, in 240 consecutive very low-birth-weight (VLBW) neonates prenatally classified as growth restricted (IUGR; n = 100) or appropriate for gestational age (n = 140).RESULTS:
Among the 214 surviving neonates, neurological follow-up was available in 163. ANDO was present in 46 children (28%). At multivariate analysis, only gestational age at delivery was independently related to the composite outcome (p < 0.001, odds ratio = 0.69, 95% confidence interval 0.59, 0.81), whereas diagnosis of IUGR was not.CONCLUSION:
Only gestational age at delivery was significantly associated with composite adverse outcome in VLBW preterm infants.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Recém-Nascido Prematuro
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Deficiências do Desenvolvimento
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Recém-Nascido de muito Baixo Peso
Tipo de estudo:
Etiology_studies
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Incidence_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Female
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Humans
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Male
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Newborn
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Pregnancy
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article