Preclinical pharmacokinetic and pharmacodynamic evaluation of novel anticancer agents, ON01910.Na (Rigosertib, Estybon&#8482;) and ON013105, for brain tumor chemotherapy.

Nuthalapati, Silpa; Zhou, Qingyu; Guo, Ping; Lv, Hua; Cosenza, Stephen; Reddy, M V Ramana; Reddy, E Premkumar; Gallo, James M

Preclinical pharmacokinetic and pharmacodynamic evaluation of novel anticancer agents, ON01910.Na (Rigosertib, Estybon™) and ON013105, for brain tumor chemotherapy.

Nuthalapati, Silpa; Zhou, Qingyu; Guo, Ping; Lv, Hua; Cosenza, Stephen; Reddy, M V Ramana; Reddy, E Premkumar; Gallo, James M.

Afiliação

Nuthalapati S; Department of Pharmaceutical Sciences, School of Pharmacy, Temple University, Philadelphia, Pennsylvania 19140, USA.

Pharm Res ; 29(9): 2499-511, 2012 Sep.

Article em En | MEDLINE | ID: mdl-22678771

Assuntos

Antineoplásicos/uso terapêutico; Neoplasias Encefálicas/tratamento farmacológico; Animais; Antineoplásicos/farmacocinética; Antineoplásicos/farmacologia; Cromatografia Líquida; Avaliação Pré-Clínica de Medicamentos; Camundongos; Espectrometria de Massas em Tandem

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Antineoplásicos Limite: Animals Idioma: En Ano de publicação: 2012 Tipo de documento: Article

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