MR-guided stereotactic laser ablation of epileptogenic foci in children.
Epilepsy Behav
; 24(4): 408-14, 2012 Aug.
Article
em En
| MEDLINE
| ID: mdl-22687387
ABSTRACT
OBJECTIVE:
For about 30% of epilepsy patients, pharmaceutical therapy fails to control their seizures. MR-guided laser interstitial thermal therapy (MRgLITT) allows for real-time thermal monitoring of the ablation process and feedback control over the laser energy delivery. We report on minimally invasive surgical techniques of MRgLITT and short-term follow-up results from the first five pediatric cases in which this system was used to ablate focal epileptic lesions.METHODS:
We studied the patients with MRI of the brain, localized the seizure with video-EEG and used the Visualase Thermal Therapy 25 System for laser ablation of their seizure foci.RESULTS:
All 5 patients are seizure free and there were no complications as of 2-13-month follow-up.CONCLUSION:
MR-guided laser interstitial thermal therapy has a significant potential to be a minimally invasive alternative to more conventional techniques to surgically treat medically refractory epilepsy in children.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Imageamento por Ressonância Magnética
/
Técnicas Estereotáxicas
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Epilepsia
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Terapia a Laser
Tipo de estudo:
Observational_studies
/
Prognostic_studies
Limite:
Adolescent
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Child
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Child, preschool
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Female
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Humans
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Male
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article