Hepatotoxicity associated with dietary energy supplements: use and abuse by young athletes.
Ann Hepatol
; 11(4): 564-9, 2012.
Article
em En
| MEDLINE
| ID: mdl-22700641
ABSTRACT
In recent years there has been a significant increase in the consumption of dietary energy supplements (DES) associated with the parallel advertising against obesity and favoring high physical performance. We present the case and outcome of a young patient who developed acute mixed liver injury (hepatocellular and cholestatic) after ingestion of various "over the counter" products to increase muscle mass and physical performance (NO Xplode®, creatine, L-carnitine, and Growth Factor ATN®). The diagnosis was based on the exclusion of other diseases and liver biopsy findings. The dietary supplement and herbal multivitamins industry is one with the highest growth rates in the market, with annual revenues amounting to billions and constantly lacking scientific or reproducible evidence about the efficacy and/or safety of the offered products. Furthermore, and contrary to popular belief, different forms of injury associated with these natural substances have been documented particularly in the liver, supporting the need of a more strict regulation.
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Base de dados:
MEDLINE
Assunto principal:
Colestase
/
Suplementos Nutricionais
/
Medicamentos sem Prescrição
/
Desempenho Atlético
/
Doença Hepática Induzida por Substâncias e Drogas
/
Atletas
/
Substâncias para Melhoria do Desempenho
/
Fígado
Tipo de estudo:
Diagnostic_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article