The local immunological microenvironment in colorectal cancer as a prognostic factor for treatment decisions in the clinic: The way ahead.

ABSTRACT

Analysis of the local immunological microenvironment in colorectal cancer lesions yielded prognostic markers. Harnessing these insights for clinical application however requires the use of sophisticated technology and algorithms, especially the robust and reproducible quantification of immune cells. These technologies are available and will allow individualized treatment decisions beyond the current standard.