The M5nr: a novel non-redundant database containing protein sequences and annotations from multiple sources and associated tools.
BMC Bioinformatics
; 13: 141, 2012 Jun 21.
Article
em En
| MEDLINE
| ID: mdl-22720753
ABSTRACT
BACKGROUND:
Computing of sequence similarity results is becoming a limiting factor in metagenome analysis. Sequence similarity search results encoded in an open, exchangeable format have the potential to limit the needs for computational reanalysis of these data sets. A prerequisite for sharing of similarity results is a common reference. DESCRIPTION We introduce a mechanism for automatically maintaining a comprehensive, non-redundant protein database and for creating a quarterly release of this resource. In addition, we present tools for translating similarity searches into many annotation namespaces, e.g. KEGG or NCBI's GenBank.CONCLUSIONS:
The data and tools we present allow the creation of multiple result sets using a single computation, permitting computational results to be shared between groups for large sequence data sets.
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Base de dados:
MEDLINE
Assunto principal:
Software
/
Bases de Dados de Proteínas
Tipo de estudo:
Risk_factors_studies
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article