Structure of the RBD-PRDI fragment of the antiterminator protein GlcT.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 68(Pt 7): 751-6, 2012 Jul 01.
Article
em En
| MEDLINE
| ID: mdl-22750856
ABSTRACT
GlcT is a transcriptional antiterminator protein that is involved in regulation of glucose metabolism in Bacillus subtilis. Antiterminator proteins bind specific RNA sequences, thus preventing the formation of overlapping terminator stem-loops. The structure of a fragment (residues 3-170) comprising the RNA-binding domain (RBD) and the first regulatory domain (PRDI) of GlcT was solved at 2.0â
Å resolution with one molecule in the asymmetric unit. The two domains are connected by a helical linker. Their interface is mostly constituted by hydrophobic interactions.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Bacillus subtilis
/
Proteínas de Bactérias
/
Fatores de Transcrição
/
Proteínas de Ligação a RNA
Tipo de estudo:
Prognostic_studies
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article