Expression, purification, crystallization and preliminary crystallographic analysis of the phosphoglycerate kinase from Acinetobacter baumannii.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 68(Pt 7): 790-2, 2012 Jul 01.
Article
em En
| MEDLINE
| ID: mdl-22750866
ABSTRACT
Acinetobacter baumannii is a common multidrug-resistant clinical pathogen that is often found in hospitals. The A. baumannii phosphoglycerate kinase (AbPGK) is involved in the key energy-producing pathway of glycolysis and presents a potential target for antibiotic development. AbPGK has been expressed and purified; it was crystallized using lithium sulfate as the precipitant. The AbPGK crystals belonged to space group P222(1). They diffracted to a resolution of 2.5â
Å using synchrotron radiation at the Canadian Light Source.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Fosfoglicerato Quinase
/
Acinetobacter baumannii
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article