Imaging features of idiopathic intracranial hypertension, including a new finding: widening of the foramen ovale.
Acta Radiol
; 53(6): 682-8, 2012 Jul.
Article
em En
| MEDLINE
| ID: mdl-22761347
ABSTRACT
BACKGROUND:
Idiopathic intracranial hypertension (IIH) is a clinical disorder of unknown etiology manifesting with increased intracranial pressure in the absence of hydrocephalus, an underlying mass lesion, and demonstrating normal cerebrospinal fluid composition. IIH may exhibit several non-specific imaging findings including an empty sella, posterior globe flattening, tortuosity of the optic nerve, and optic nerve sheath distention.PURPOSE:
To introduce widening of the foramen ovale as a new imaging marker for IIH. MATERIAL ANDMETHODS:
IIH is a syndrome which may exhibit several previously described non-specific imaging findings including an empty sella, posterior globe flattening, tortuosity of the optic nerve, and optic nerve sheath distention. We hypothesize that chronically elevated cerebrospinal fluid pressure can lead to osseous erosions and we propose widening of the foramen ovale as a new imaging marker for IIH.RESULTS:
Average foramen ovale sizes were increased in patients with IIH compared to controls (30.03 ± 7.00 mm(2) vs. 24.21 ± 5.97 mm(2), P < 0.001). For a cut-off value of 30 mm(2), the sensitivity of FO area to detect IIH was 50%, with 81% specificity. Classic findings were significantly more common in patients with IIH compared to controls including empty sella (65.9% vs. 0%), posterior globe flattening (65.9% vs. 4.5%), vertical tortuosity of the optic nerve (54.5% vs. 9.1%), and optic nerve sheath distention (52.3% vs. 11.4%, all P values < 0.001).CONCLUSION:
Our study confirms the association of several classic imaging findings with IIH and supports widening of the foramen ovale as an additional imaging marker which may be incorporated into the evaluation of patients suspected to have this condition.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Pseudotumor Cerebral
/
Imageamento por Ressonância Magnética
/
Tomografia Computadorizada por Raios X
/
Forame Oval
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article