Risk of invasive breast cancer and ductal carcinoma in situ in women with atypical papillary lesions of the breast.
Breast J
; 18(5): 475-8, 2012 Sep.
Article
em En
| MEDLINE
| ID: mdl-22776070
ABSTRACT
Benign papillary lesions of the breast include papilloma and papillomatosis. A retrospective analysis of patients with a papillary breast lesion diagnosed between October 1992 and December 2009 was performed. Patients were excluded if they had a previous or concurrent diagnosis of invasive or in situ cancer or less than 6 months of follow-up. The Kaplan-Meier method was used to determine the risk of developing subsequent malignancy. The log rank test was used to compare groups of patients. Median follow-up for the 167 patients included in the study was 4.6 years. Fifty-one patients had a papillary lesion with atypia and 116 patients had a papillary lesion without atypia. Patients with a papillary lesion with atypia were more likely to develop invasive or in situ breast cancer with a 5 year risk of 13.0% versus 4.6% in patients with no atypia (p = 0.03).
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Papiloma
/
Neoplasias da Mama
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Carcinoma Intraductal não Infiltrante
/
Glândulas Mamárias Humanas
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
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Middle aged
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article