The 5-HT immunoreactive innervation of the Helix procerebrum.
Acta Biol Hung
; 63 Suppl 2: 96-103, 2012.
Article
em En
| MEDLINE
| ID: mdl-22776481
ABSTRACT
In the procerebrum of terrestrial snails, 5-HT is a key modulatory substance of the generation of synchronous oscillatory activity and odor learning capability. In this study, we have analyzed the characteristics of the 5-HT-immunoreactive (5-HT-IR) innervation of the distinct anatomical regions of the procerebrum of Helix pomatia, applying correlative light- and electron microscopic immunocytochemistry. A dense network of 5-HT-IR innervation was demonstrated in the cell body layer, meanwhile a varicose fiber system of different density occurred in the different neuropil regions. At the ultrastructural level, labeled varicosities were found to contact both procerebral cell bodies, and different unlabeled axon profiles in the neuropils. The labeled structures established mostly close non-specialized membrane contacts with the postsynaptic profiles. The overall dense distribution of 5-HT-IR innervation supports a general modulatory role of 5-HT in processing different olfactory events.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Serotonina
/
Sistema Nervoso Central
/
Caracois Helix
Limite:
Animals
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article