Epidemiology of influenza A (H1N1)pdm09-associated deaths in the United States, September-October 2009.
Influenza Other Respir Viruses
; 6(6): e169-77, 2012 Nov.
Article
em En
| MEDLINE
| ID: mdl-22805001
ABSTRACT
BACKGROUND:
From April to July 2009, the United States experienced a wave of influenza A (H1N1)pdm09 virus (H1N1pdm09) infection. The majority of the deaths during that period occurred in persons <65 years of age with underlying medical conditions.OBJECTIVE:
To describe the epidemiology of H1N1pdm09-associated deaths in the US during the fall of 2009.METHODS:
We collected demographic, medical history, and cause of death information on a nationally representative, stratified random sample of 323 H1N1pdm09-associated deaths that occurred during September 1-October 31, 2009.RESULTS:
Data were available for 302/323 (93%) deaths. Most cases (74%) were 18-64 years of age and had ≥ 1 underlying medical condition (72%). Among cases aged <18 years, 16/43 (37%) had a chronic lung disease, and 15/43 (35%) a neurological disorder; among cases aged ≥ 18 years, 94/254 (37%) had a chronic lung disease and 84/254 (33%) had a metabolic disorder. The median number of days between symptom onset and death was six among children (range, 1-48) and 12 among adults (range, 0-109). Influenza antiviral agents were prescribed for 187/268 (70%) of cases, but only 48/153 (31%) received treatment within 2 days of illness onset.CONCLUSIONS:
The characteristics of H1N1pdm09 deaths identified during the fall of 2009 were similar to those occurring April-July 2009. While most cases had conditions that were known to increase the risk for severe outcomes and were recommended to receive antiviral therapy, a minority of cases received antivirals early in the course of illness.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Influenza Humana
/
Vírus da Influenza A Subtipo H1N1
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
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Screening_studies
Limite:
Adolescent
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Adult
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Aged
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Aged80
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Child
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Child, preschool
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Female
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Humans
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Infant
/
Male
País como assunto:
America do norte
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article