[A novel C27-steroidal glycoside sulfate from Liriope graminifolia].
Yao Xue Xue Bao
; 47(5): 619-23, 2012 May.
Article
em Zh
| MEDLINE
| ID: mdl-22812006
ABSTRACT
An unusual novel C27-steroidal glycoside sulfate was isolated from the underground organs of Liriope graminifolia (Linn.) Baker with three known compounds. Their chemical structures were determined by spectral analysis, including HR-MS, 1D and 2D NMR as (25S)-ruscogenin 1-sulfate-3-O-alpha-L-rhamnopyranoside (1), (25S)-ruscogenin 1-O-beta-D-xylopyranosyl-3-O-alpha-L-rhamnopyranoside (2), hesperidin (3), and 4', 7-dihydroxy-5-methoxyflavanone (4). Compound 1 has cytotoxic activities against K562 and HL60 cells with IC50 values of 18.6 microg x mL(-1) and 16.5 microg x mL(-1), respectively.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Espirostanos
/
Medicamentos de Ervas Chinesas
/
Liriope (Planta)
/
Glicosídeos
/
Antineoplásicos Fitogênicos
Limite:
Humans
Idioma:
Zh
Ano de publicação:
2012
Tipo de documento:
Article