Ilelic acids A and B, two unusual triterpenes with a seven-membered ring from Ilex latifolia.
Org Lett
; 14(16): 4102-5, 2012 Aug 17.
Article
em En
| MEDLINE
| ID: mdl-22834418
ABSTRACT
Two unusual triterpenes, ilelic acids A (1) and B (2), together with their biosynthetic related compounds ilelic acids C (3) and D (4) were isolated from the leaves of Ilex latifolia. Their structures with absolute configurations were elucidated by spectroscopic analysis and modified Mosher's method. The plausible biogenetic pathway of 1 and 2 is proposed. These triterpenes exhibited a potent inhibitory effect on MCF-7 and MDA-MB-231 cells.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Triterpenos
/
Ilex
/
Antineoplásicos Fitogênicos
Limite:
Female
/
Humans
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article