[Clinical value of determining the levels of renin, aldosterone and vasopressin in newborn infants in critical conditions]. / Klinicheskoe znachenie opredeleniia renina, al'dosterona i vazopressina pri kriticheskikh sostoianiiakh u novorozhdennykh detei.

ABSTRACT

The concentrations of aldosterone, vasopressin and plasma renin activity were measured in cord blood and on days 1, 3 and 5 of life in 71 newborn infants from the risk group at the development of critical conditions. Vasopressin was discovered to play a substantial role in the development of critical conditions. The lack of a considerable vasopressin ejection in response to a delivery trouble and the growth of its concentration by day 5 of life are prognostically unfavourable. Hyperactivity of the renin-aldosterone system determines the newborns' proneness to liquid and sodium retention.