A chemoselective, one-pot transformation of aldehydes to nitriles.
J Org Chem
; 77(20): 9334-7, 2012 Oct 19.
Article
em En
| MEDLINE
| ID: mdl-22928794
ABSTRACT
This paper describes a procedure for direct conversion of aldehydes to nitriles using O-(diphenylphosphinyl)hydroxylamine (DPPH). Aldehydes are smoothly transformed to their corresponding nitriles by heating with DPPH in toluene. The reaction can be accomplished in the presence of alcohol, ketone, ester, or amine functionality.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Aldeídos
/
Nitrilas
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article