Russian "successful" clone B0/W148 of Mycobacterium tuberculosis Beijing genotype: a multiplex PCR assay for rapid detection and global screening.
J Clin Microbiol
; 50(11): 3757-9, 2012 Nov.
Article
em En
| MEDLINE
| ID: mdl-22933595
ABSTRACT
We describe a multiplex PCR assay to detect the Mycobacterium tuberculosis Beijing genotype variant B0/W148, which is considered a "successful" clone of M. tuberculosis, widespread in Russia. Specificity and sensitivity of the assay were 100% based on the analysis of a collection of 516 M. tuberculosis isolates of different genotypes and origins. This assay may be used for accurate and simple detection and surveillance of this clinically and epidemiologically important variant of M. tuberculosis.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Tuberculose
/
Técnicas Bacteriológicas
/
Técnicas de Diagnóstico Molecular
/
Reação em Cadeia da Polimerase Multiplex
/
Mycobacterium tuberculosis
Tipo de estudo:
Diagnostic_studies
/
Evaluation_studies
/
Prognostic_studies
/
Screening_studies
Limite:
Humans
País como assunto:
Asia
/
Europa
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article