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Excretion of himantane and its metabolites with the urine and feces in rats.
Litvin, E A; Bastrygin, D V; Kolyvanov, G B; Alekseyev, K V; Zherdev, V P.
Afiliação
  • Litvin EA; Laboratory of Pharmacokinetics, V. V. Zakusov Institute of Pharmacology, the Russian Academy of Medical Sciences, Moscow, Russia. zlanomar@gmail.com
Bull Exp Biol Med ; 153(4): 481-2, 2012 Aug.
Article em En, Ru | MEDLINE | ID: mdl-22977850
ABSTRACT
The levels of himantane and its metabolites in daily urine and feces of rats were measured after intraperitoneal and oral dose of 25 mg/kg. The injected dose of the initial substance and 1.3% its metabolites were eliminated with excrements within 24 h after administration via both routes 0.23%.
Assuntos
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Base de dados: MEDLINE Assunto principal: Adamantano / Antiparkinsonianos Limite: Animals Idioma: En / Ru Ano de publicação: 2012 Tipo de documento: Article
Buscar no Google
Base de dados: MEDLINE Assunto principal: Adamantano / Antiparkinsonianos Limite: Animals Idioma: En / Ru Ano de publicação: 2012 Tipo de documento: Article