Otitis media in infancy and the development of asthma and atopic disease.
Curr Allergy Asthma Rep
; 12(6): 547-50, 2012 Dec.
Article
em En
| MEDLINE
| ID: mdl-23011595
ABSTRACT
Otitis media is a frequent respiratory infection of early childhood and it is important to fully understand the long-term complications and sequelae. Literature examining otitis media in early childhood and subsequent development of atopic disease is sparse despite there being vast literature on the association between respiratory infections and atopic disease. Current data support the hypothesis that otitis media infections in early life, especially frequent or severe infections, influence the developing immune system, resulting in increased risk for asthma. Recent findings have also reported an association between otitis media and eczema. Atopic children and those with a family history of atopy appear to be at greater risk. Future work should investigate the specific mechanisms involved. It is possible that vaccines and preventive strategies aimed at reducing the burden of otitis media could also reduce the burden of childhood asthma and atopic disease.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Otite Média
/
Infecções Respiratórias
/
Asma
/
Hipersensibilidade Imediata
Tipo de estudo:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Child
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Child, preschool
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Humans
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Infant
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article