Intra-abdominal fat area is a predictor for new onset of individual components of metabolic syndrome: MEtabolic syndRome and abdominaL ObesiTy (MERLOT study).
Proc Jpn Acad Ser B Phys Biol Sci
; 88(8): 454-61, 2012.
Article
em En
| MEDLINE
| ID: mdl-23060233
ABSTRACT
OBJECTIVE:
To investigate the significance of intra-abdominal fat area (IAFA) on new onset of individual components of the metabolic syndrome high blood pressure, dyslipidemia, or hyperglycemia.METHODS:
We conducted a longitudinal study using checkup data of a hospital from 1994 to 2010. Of 25,255 subjects, we examined 1,380 Japanese, who underwent computed tomography to measure IAFA and had no metabolic syndrome components at baseline.RESULTS:
During 3.6 years of the mean follow-up period, one of metabolic syndrome components occurred in 752 subjects. Of three components, high blood pressure was more prevalent. The multiple Cox regression analysis disclosed that IAFA is significantly associated with onset of metabolic syndrome components (HR 1.05 per 10 cm(2), 95%CI 1.03-1.07). This finding was independent of BMI, and significant even in non-obese individuals with body mass index <25 kg/m(2).CONCLUSIONS:
MERLOT study demonstrates that IAFA is an independent predictor for new onset of individual components of the metabolic syndrome, even in non-obese healthy Japanese.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Síndrome Metabólica
/
Gordura Intra-Abdominal
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Obesidade Abdominal
Tipo de estudo:
Etiology_studies
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Observational_studies
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Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
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Female
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Humans
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Male
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Middle aged
País como assunto:
Asia
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article