Synthesis and in vitro antimicrobial activity of novel 2-(3-oxo-1,3-diarylpropylthio)acetic acid derivatives.
Acta Pol Pharm
; 69(5): 893-900, 2012.
Article
em En
| MEDLINE
| ID: mdl-23061285
ABSTRACT
A series of novel 2-(3-oxo-1,3-diarylpropylthio)acetic acid derivatives (3a-l) were prepared by base catalyzed addition of thioglycolic acid to chalcones (1a-l). The antibacterial activities of synthesized compounds were screened against human pathogenic microorganisms by employing the disk-diffusion technique. For the active compounds, also minimum inhibitory concentrations (MICs) were determined.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Tioglicolatos
/
Anti-Infecciosos
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article