Prevalence of genomic island PAPI-1 in clinical isolates of Pseudomonas aeruginosa in Iran.
Southeast Asian J Trop Med Public Health
; 43(2): 431-5, 2012 Mar.
Article
em En
| MEDLINE
| ID: mdl-23082593
ABSTRACT
Pseudomonas aeruginosa, a gram-negative rod-shaped bacterium, is an opportunistic pathogen, which causes various serious diseases in humans and animals. The aims of this study were to evaluate of the presence of genomic island PAPI-1 in Pseudomonas aeruginosa isolated from Reference Laboratory of Ilam, Milad Hospital and Emam Khomeini Hospital, Iran and to study the frequency of extended spectrum beta-lactamases (ESBLs) among isolates. Forty-eight clinical isolates of P. aeruginosa were obtained during April to September 2010, and were evaluated for ESBLs by screening and confirmatory disk diffusion methods and PAPI-1 by PCR. Fifteen of 48 P. aeruginosa isolates were positive for ESBLs and 17 isolates positive for PAPI-1. This was first study of the prevalence of PAPI-1 in clinical isolates of P. aeruginosa in Iran, showing that most of PAPI-1 positive strains had high levels of antibiotic resistance and produced ESBLs.
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Base de dados:
MEDLINE
Assunto principal:
Pseudomonas aeruginosa
/
Ilhas Genômicas
Tipo de estudo:
Prevalence_studies
/
Risk_factors_studies
Limite:
Humans
País como assunto:
Asia
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article