[Expression of serum sICAM-1 in patients with primary hepatocellular carcinoma and its relationship with liver fibrosis].
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
; 28(2): 181-2, 2012 Feb.
Article
em Zh
| MEDLINE
| ID: mdl-23162921
ABSTRACT
AIM:
To explore the clinical value of serum soluble intercellular adhesion molecule-1 (sICAM-1) in patients with primary hepatocellular carcinoma (PHC) and its relationship with liver fibrosis.METHODS:
The serun sICAM-1, PC III, IV-C, LN and HA level of 45 cases of patients with PHC, 30 cases of benign tumor and 35 cases of healthy people were determined by ELISA, the relationship between sICAM-1 and liver fibrosis was analyzed.RESULTS:
The serum sICAM-1, PC III, IV-C, LN and HA levels of the PHC group were significantly higher than that of the benign tumor group and normal control group, compared the difference was significant (P<0.05); The serum markers was no significant difference between the benign tumor group and normal control group (P>0.05); The serum sICAM-1 was positively correlated with the PC III, IV-C, LN and HA (γ= 0.683, 0.575, 0.573 and 0.539, P<0.05).CONCLUSION:
Detection of serum sICAM-1 has important clinical significance for assessing the PHC patient's condition, early diagnosing and treating liver cancer.
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Base de dados:
MEDLINE
Assunto principal:
Carcinoma Hepatocelular
/
Molécula 1 de Adesão Intercelular
/
Cirrose Hepática
/
Neoplasias Hepáticas
Tipo de estudo:
Prognostic_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Zh
Ano de publicação:
2012
Tipo de documento:
Article