Reconstruction of an extensive peri-orbital defect secondary to mucormycosis in a patient with myelodysplasia.
J Plast Reconstr Aesthet Surg
; 66(3): e69-71, 2013 Mar.
Article
em En
| MEDLINE
| ID: mdl-23232448
ABSTRACT
We present the case of a 68-year old gentleman with previously diagnosed myelodysplastic syndrome with pancytopenia who presented with exophthalmia, rhinorrhea, and ophthalmoplegia. Nasal endoscopy revealed black necrotic lesions. He was diagnosed with rhino-orbital mucormycosis and commenced on intravenous antifungals. Despite this therapy he progressed to have total unilateral loss of visual acuity and cutaneous necrosis. He underwent emergency orbital exenteration and extensive cheek and sinus debridement. Necrotic lesions were found in the orbit, the maxillary and ethmoidal sinuses. He underwent reconstruction of this defect using a free myocutaneous ALT flap with a segment of vastus lateralis. Prior to surgery his anemia and thrombocytopenia were addressed with packed red cell and platelet transfusions as well as preoperative thromboelastography (TEG) to measure functional fibrinogen to platelet ratio. Intraoperative platelet administration was guided by repeated TEG analysis. There were no significant intraoperative or postoperative bleeding complications and both flap and donor site healed unremarkably. Few reports exist in the literature related to free tissue transfer in patients with hematological disorders but low platelet count has been implicated in an increased complication rate.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doenças Orbitárias
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Síndromes Mielodisplásicas
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Procedimentos de Cirurgia Plástica
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Retalhos de Tecido Biológico
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Mucormicose
Tipo de estudo:
Etiology_studies
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Observational_studies
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Prognostic_studies
Limite:
Aged
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Humans
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Male
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article