[Clinical-diagnostic hit rates and differential diagnoses depending on the sampling site of 2109 presumptively malignant canine and feline tumour submissions]. / Klinisch-diagnostische Trefferquoten und Differenzialdiagnosen bei 2109 kaninen und felinen Tumorproben mit Malignitätsverdacht. Evaluierung in Abhängigkeit der Entnahmelokalisation.

OBJECTIVE: The frequency of correct clinical presumptive diagnosis and the spectrum of important differential diagnoses were investigated in common canine and feline malignant tumours. MATERIAL AND METHODS: Based on 2109 presumptive malignant tumour samples submitted to the Institute of Veterinary Pathology of the Justus-Liebig-University, Giessen, the hit rates of the presumed diagnoses of the submitting veterinarians and the actual histopathological diagnosis were calculated for the specific sampling sites. These hit rates were statistically evaluated for significant deviations between the different sampling sites using the chi-square test and Fisher's exact test. Additionally, the more common differential diagnoses with respect to the sampling site were established. RESULTS: This compilation of histopathological diagnoses, with respect to the varying sampling sites, combined with the hit rates of the presumed diagnoses of the submitting veterinarians, yields quantitative knowledge on the frequency of occurrence, correct clinical diagnosis and macroscopic appearance of the malignant tumours investigated. The correctness of the presumptive clinical diagnosis largely depends on tumour type and localization. For the more frequent tumours, it varies from 19% to 83%. CONCLUSION AND CLINICAL RELEVANCE: The results show the importance of a histopathological evaluation of all tumour samples as the presumptive clinical diagnosis based on appearance only corresponds in a few cases with the histopathological diagnosis.