Prevalence and impact of past history of food allergy in atopic dermatitis.
Allergol Int
; 62(1): 105-12, 2013 Mar.
Article
em En
| MEDLINE
| ID: mdl-23267210
ABSTRACT
BACKGROUND:
Increases in allergic diseases have been reported from various epidemiological surveys. However, a few reports demonstrate the comorbidity of food allergy (FA) and allergic march. The aim of this study was to assess the prevalence and comorbidity of allergic diseases in Japanese students.METHODS:
First-year students (n = 3,321; 2,209 male and 1,112 female) at Osaka University were asked about allergic diseases using postal interview sheets. Personal and family histories of doctor-diagnosed allergic diseases, clinical courses, and aggravating factors were included in the questionnaires.RESULTS:
The lifetime prevalence of allergic rhinitis (AR), atopic dermatitis (AD), bronchial asthma (BA), and FA was 35.7%, 16.5%, 9.9%, and 7.0%, respectively. Disease-specific family histories existed for AR, AD, and BA. There was a positive correlation between the number of family histories of allergic disease and comorbidity (R = 0.370, P < 0.001). Comorbidity with AD significantly lowered the onset age of both BA (P = 0.010) and AR (P < 0.001). In addition, the onset age of AD was remarkably lowered by comorbidity with FA (P < 0.001). Comorbidity with FA was the highest risk factor for the progression of allergic march. Although most students showed improvement in AD, BA, and AR over time, the peak recurrence period was observed in adolescence.CONCLUSIONS:
These findings indicate that AD associated with FA accelerates the subsequent progression of allergic march. Early appropriate management for genetically high-risk groups is important for the prevention of allergic march.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Dermatite Atópica
/
Hipersensibilidade Alimentar
Tipo de estudo:
Etiology_studies
/
Observational_studies
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Prevalence_studies
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Risk_factors_studies
Limite:
Adolescent
/
Adult
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Female
/
Humans
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Male
País como assunto:
Asia
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article