[Clinical study on spanishneedles leaves in treatment of middle and severe xerophthalmia of menopausal females].
Zhongguo Zhong Yao Za Zhi
; 37(19): 2985-9, 2012 Oct.
Article
em Zh
| MEDLINE
| ID: mdl-23270247
ABSTRACT
OBJECTIVE:
To investigate the clinical effect of spanishneedles leaves on middle and severe xerophthalmia of menopausal females.METHOD:
This study was a prospective random controlled trial. Ninty-six menopausal females diagnosed with xerophthalmnia (aged from 40 to 50) were randomly divided into in two groups group A' the spanishneedles leaves group (n=48) and group B' the control group (n=48). Both groups were treated with Forte eye drops. All patients were detected at 3, 7, 28 h before and after treatment to evaluate subjective symptoms, OSDI and four tear film indicators. Variance analysis and differential analysis on sample average or median were made on both groups before and after treatment.RESULT:
There were no significant difference in symptom and diction indicators between both groups before treatment. For 28 d after treatment, among middle and severe xerophthalmia samples of the spanishneedles leaves group, the mean differences showed significant improvement compared with that before treatment , OSDI and four tear film indicators also showed improvement to varying degrees. For 28 d after treatment, among middle and severe xerophthalmia samples of the vitamin C group, the mean differences showed no significant improvement compared with that before treatment , OSDI and four tear film indicators also showed no remarkable improvement. There were significant differences in OSDI, BUT, SIT, height of tear meniscus and FL between both groups.CONCLUSION:
Spanishneedles leaves can effectively improve symposiums and signs of middle and severe xerophthalmia among menopausal females and thus showing clinical significance to some extent.
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Eixos temáticos:
Pesquisa_clinica
Base de dados:
MEDLINE
Assunto principal:
Plantas Medicinais
/
Menopausa
/
Xeroftalmia
/
Folhas de Planta
Tipo de estudo:
Clinical_trials
Limite:
Adult
/
Female
/
Humans
/
Middle aged
Idioma:
Zh
Ano de publicação:
2012
Tipo de documento:
Article