Genome-wide data substantiate Holocene gene flow from India to Australia.
Proc Natl Acad Sci U S A
; 110(5): 1803-8, 2013 Jan 29.
Article
em En
| MEDLINE
| ID: mdl-23319617
ABSTRACT
The Australian continent holds some of the earliest archaeological evidence for the expansion of modern humans out of Africa, with initial occupation at least 40,000 y ago. It is commonly assumed that Australia remained largely isolated following initial colonization, but the genetic history of Australians has not been explored in detail to address this issue. Here, we analyze large-scale genotyping data from aboriginal Australians, New Guineans, island Southeast Asians and Indians. We find an ancient association between Australia, New Guinea, and the Mamanwa (a Negrito group from the Philippines), with divergence times for these groups estimated at 36,000 y ago, and supporting the view that these populations represent the descendants of an early "southern route" migration out of Africa, whereas other populations in the region arrived later by a separate dispersal. We also detect a signal indicative of substantial gene flow between the Indian populations and Australia well before European contact, contrary to the prevailing view that there was no contact between Australia and the rest of the world. We estimate this gene flow to have occurred during the Holocene, 4,230 y ago. This is also approximately when changes in tool technology, food processing, and the dingo appear in the Australian archaeological record, suggesting that these may be related to the migration from India.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Genoma Humano
/
Fluxo Gênico
/
Migração Humana
/
Genética Populacional
Tipo de estudo:
Prognostic_studies
Limite:
Humans
País como assunto:
Africa
/
Asia
/
Oceania
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article