An update on the prevalence of cerebral palsy: a systematic review and meta-analysis.
Dev Med Child Neurol
; 55(6): 509-19, 2013 Jun.
Article
em En
| MEDLINE
| ID: mdl-23346889
ABSTRACT
AIMS:
The aim of this study was to provide a comprehensive update on (1) the overall prevalence of cerebral palsy (CP); (2) the prevalence of CP in relation to birthweight; and (3) the prevalence of CP in relation to gestational age.METHOD:
A systematic review and meta-analysis was conducted and reported, based on the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) statement. Population-based studies on the prevalence of CP in children born in 1985 or after were selected. Statistical analysis was carried out using computer package R, version 2.14.RESULTS:
A total of 49 studies were selected for this review. The pooled overall prevalence of CP was 2.11 per 1000 live births (95% confidence interval [CI] 1.98-2.25). The prevalence of CP stratified by gestational age group showed the highest pooled prevalence to be in children weighing 1000 to 1499g at birth (59.18 per 1000 live births; 95% CI 53.06-66.01), although there was no significant difference on pairwise meta-regression with children weighing less than 1000g. The prevalence of CP expressed by gestational age was highest in children born before 28 weeks' gestation (111.80 per 1000 live births; 95% CI 69.53-179.78; p<0.0327).INTERPRETATION:
The overall prevalence of CP has remained constant in recent years despite increased survival of at-risk preterm infants.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Paralisia Cerebral
Tipo de estudo:
Etiology_studies
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Prevalence_studies
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Risk_factors_studies
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Systematic_reviews
Limite:
Child
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Child, preschool
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Humans
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Infant
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Newborn
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article