Dynamics of traction stress field during cell division.
Phys Rev Lett
; 109(24): 248110, 2012 Dec 14.
Article
em En
| MEDLINE
| ID: mdl-23368393
ABSTRACT
We report a quantitative measurement of traction stress exerted by dividing eukaryotic cells. The stress field was highly dynamic and sequentially changed as follows (1) strong and localized as two spots, (2) weak and broadly distributed, and (3) strong and localized as four spots. At the final stage of cytokinesis, the dividing cells exerted strong tensile force on the intercellular bridge. The asymmetry of the traction stress and the orientation of the division axis matched throughout the division process, suggesting the possible role of the mechanical force as a "store" of the orientational information.
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Base de dados:
MEDLINE
Assunto principal:
Divisão Celular
/
Modelos Biológicos
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article