[Paradigm shifts in aortic pathology: clinical and therapeutic implications. Biology and pathology of the aortic wall]. / Cambi di paradigma in tema di aorta: implicazioni cliniche e terapeutiche La biopatologia dell'aorta.

Improved knowledge of the structure and function of the aortic wall, as well as its pathophysiology and histopathology, will result in an increasing impact on clinical evaluation and treatment of thoracic aortic diseases. This opinion paper highlights the main "paradigmatic shifts" in this field, providing cardiologists with some novel clues for the clinical approach to patients with thoracic aortic disease.