Long-term dynamics of CA1 hippocampal place codes.
Nat Neurosci
; 16(3): 264-6, 2013 Mar.
Article
em En
| MEDLINE
| ID: mdl-23396101
ABSTRACT
Using Ca(2+) imaging in freely behaving mice that repeatedly explored a familiar environment, we tracked thousands of CA1 pyramidal cells' place fields over weeks. Place coding was dynamic, as each day the ensemble representation of this environment involved a unique subset of cells. However, cells in the â¼15-25% overlap between any two of these subsets retained the same place fields, which sufficed to preserve an accurate spatial representation across weeks.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Potenciais de Ação
/
Cálcio
/
Células Piramidais
/
Região CA1 Hipocampal
Limite:
Animals
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article