The spectrum of movement disorders in children with anti-NMDA receptor encephalitis.
Mov Disord
; 28(4): 543-7, 2013 Apr.
Article
em En
| MEDLINE
| ID: mdl-23400857
ABSTRACT
BACKGROUND:
Movement disorders are frequent but difficult to characterize in patients with anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis.METHODS:
The phenomenology of movement disorders was characterized after a detailed examination of children with anti-NMDAR-encephalitis.RESULTS:
We studied 9 children (5 females), ages 3-14 years, with confirmed anti-NMDAR-encephalitis. All patients presented with at least 1 movement disorder, including chorea (n=4), stereotypic movements (n=4), ataxia (n=3), limb dystonia (n=2), limb myorhythmia (n=2), oromandibular dystonia (n=2), facial myorhythmia, blepharospasm, opisthotonus, athetosis, and tremor (n=1, each). More than a single movement disorder was observed in 6 of these patients. Resolution of the abnormal movements was observed in all patients with immunotherapy; 1 patient improved with tetrabenazine.CONCLUSIONS:
A wide variety of movement disorders, often in combination, can be observed in children with anti-NMDAR encephalitis. Patients commonly present with more than a single movement disorder.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Receptores de N-Metil-D-Aspartato
/
Discinesias
/
Encefalite Antirreceptor de N-Metil-D-Aspartato
/
Transtornos dos Movimentos
Tipo de estudo:
Diagnostic_studies
/
Qualitative_research
Limite:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article