Two new triterpenoids from the fungus Perenniporia maackiae.

ABSTRACT

Two new triterpenoids, 3ß-(2-methoxy-oxalyloxy)-24-methylene-lanost-8-en-21-oic acid (1) and 3ß-(2-methoxy-oxalyloxy)-15α-hydroxy-24-methylene-lanost-8-en-21-oic acid (2), were isolated from cultures of the fungus Perenniporia maackiae, together with two previously known triterpenoids (3 and 4). Their structures were determined by spectroscopic methods, including 1D and 2D NMR, and MS analyses. All compounds were evaluated for their cytotoxic activities on five tumor cell lines.