Effects of smoking specified as cigarettes per day and maternal body mass index on hypertensive disorders of pregnancy.
Z Geburtshilfe Neonatol
; 217(1): 24-7, 2013 Feb.
Article
em En
| MEDLINE
| ID: mdl-23440658
ABSTRACT
BACKGROUND:
We have previously described the prevalence in pregnancy of hypertension, proteinuria, oedema and preeclampsia/eclampsia according to maternal body mass index (BMI) and smoking status. We found that these disorders were less frequent among smoking women. To investigate whether this relationship is causal or a chance finding, we here present an analysis according to BMI and smoking specified according to the number of cigarettes consumed per day. MATERIALS ANDMETHODS:
Data were from the German Perinatal Survey of 1998-2000. We classified women by BMI as underweight (BMI<18.5 kg/m2), normal weight (BMI 18.5-24.99 kg/m2), overweight (25.0-29.99 kg/m2), or obese (BMI≥30 kg/m2). Smoking was categorised as being a non-smoker or smoking 1-7, 8-14 or ≥ 15 cigarettes per day. Datasets from 433 669 singleton pregnancies with information on maternal BMI and smoking were included in the analysis.RESULTS:
In all BMI categories hypertension, moderate to severe oedema, and preeclampsia/eclampsia became less prevalent with increasing maternal cigarette consumption.CONCLUSIONS:
Dose-dependence was not convincing for proteinuria.Dose-dependence in the relationship between smoking and hypertensive disorders of pregnancy argues against a chance finding and for a causal relationship.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Pré-Eclâmpsia
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Complicações Cardiovasculares na Gravidez
/
Proteinúria
/
Fumar
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Índice de Massa Corporal
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Sobrepeso
/
Hipertensão
Tipo de estudo:
Etiology_studies
/
Incidence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
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Adult
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Female
/
Humans
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Middle aged
/
Pregnancy
País como assunto:
Europa
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article