Premorbid impairments in early-onset psychosis: differences between patients with schizophrenia and bipolar disorder.
Schizophr Res
; 146(1-3): 103-10, 2013 May.
Article
em En
| MEDLINE
| ID: mdl-23465966
ABSTRACT
BACKGROUND:
Despite the large body of research on premorbid impairments in schizophrenia, studies comparing different early-onset psychoses are scarce.AIMS:
To examine premorbid impairments in first episodes of early-onset bipolar and schizophrenia disorders.METHOD:
We compared premorbid adjustment and other premorbid variables such as IQ and developmental abnormalities in a cohort of children and adolescents (N=69) with bipolar disorder (BP) or schizophrenia (SZ) experiencing their first psychotic episode and in a healthy control group (N=91).RESULTS:
Schizophrenia patients showed more social impairment in childhood than bipolar patients (p<0.05) and healthy controls (p<0.001) and had higher rates of developmental abnormalities (p<0.05) than healthy controls. Between childhood and early adolescence, schizophrenia and bipolar patients showed a greater decline in academic adjustment than healthy controls, more specifically in adaptation to school (p<0.01).CONCLUSIONS:
Early-onset schizophrenia patients show more early social impairment than early-onset bipolar patients. Intellectual premorbid abnormalities are less specific and probably more linked to early-onset psychosis.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Transtornos Psicóticos
/
Esquizofrenia
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Psicologia do Esquizofrênico
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Transtornos do Comportamento Social
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Transtorno Bipolar
/
Deficiências do Desenvolvimento
Tipo de estudo:
Clinical_trials
/
Diagnostic_studies
/
Observational_studies
/
Screening_studies
Limite:
Adolescent
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Female
/
Humans
/
Male
País como assunto:
Europa
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article