25-hydroxyvitamin D levels in African American and Nigerian women.
Am J Hum Biol
; 25(4): 560-2, 2013.
Article
em En
| MEDLINE
| ID: mdl-23559500
ABSTRACT
OBJECTIVES:
African Americans (AA) have substantially lower levels of circulating 25-hydroxyvitamin D (25(OH)D) than whites. We compared population-based samples of 25(OH)D in women of African descent from Nigeria and metropolitan Chicago.METHODS:
One hundred women of Yoruba ethnicity from southwest Nigeria and 94 African American women from metropolitan Chicago were recruited and compared using a standardized survey protocol and the same laboratory assay for 25(OH)D.RESULTS:
Mean 25(OH)D levels were 64 nmol/l among the Nigerians and 29 nmol/l among the AA. Only 10% of the values were shared in common between the groups, and 76% of the Nigerians were above the currently defined threshold for adequate circulating 25(OH)D compared to 5% of the AA. Modest associations were seen between 25(OH)D and measures of obesity, although adjustment for these traits did not materially affect the group differences.CONCLUSION:
These data support the presumption that skin color is an adaptive trait which has evolved in part to regulate 25(OH)D. It remains undetermined, however, whether lower values observed in AA have negative health consequences.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
População Rural
/
População Urbana
/
Vitamina D
/
Deficiência de Vitamina D
/
Negro ou Afro-Americano
Limite:
Adolescent
/
Adult
/
Female
/
Humans
/
Middle aged
País como assunto:
Africa
/
America do norte
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article