Copper-catalyzed decarboxylative coupling of alkynyl carboxylates with 1,1-dibromo-1-alkenes.
J Org Chem
; 78(9): 4551-7, 2013 May 03.
Article
em En
| MEDLINE
| ID: mdl-23578212
ABSTRACT
A copper-catalyzed decarboxylative coupling reaction of potassium alkynyl carboxylates with 1,1-dibromo-1-alkenes was developed for the synthesis of unsymmetrical 1,3-diyne and 1,3,5-triyne derivatives. Diverse aryl, alkenyl, alkynyl, and alkyl substituted 1,1-dibromo-1-alkenes can react smoothly with aryl and alkyl substituted propiolates to produce unsymmetrical 1,3-diynes and 1,3,5-triynes with high selectivity and good functional group compatibility.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ácidos Carboxílicos
/
Cobre
/
Alcenos
/
Alcinos
/
Hidrocarbonetos Bromados
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article