Methods of linking mothers and infants using health plan data for studies of pregnancy outcomes.
Pharmacoepidemiol Drug Saf
; 22(7): 776-82, 2013 Jul.
Article
em En
| MEDLINE
| ID: mdl-23596095
ABSTRACT
PURPOSE:
Research on medication safety in pregnancy often utilizes health plan and birth certificate records. This study discusses methods used to link mothers with infants, a crucial step in such research.METHODS:
We describe how eight sites participating in the Medication Exposure in Pregnancy Risk Evaluation Program created linkages between deliveries, infants and birth certificates for the 2001-2007 birth cohorts. We describe linkage rates across sites, and for two sites, we compare the characteristics of populations linked using different methods.RESULTS:
Of 299,260 deliveries, 256,563 (86%; range by site, 74-99%) could be linked to infants using a deterministic algorithm. At two sites, using birth certificate data to augment mother-infant linkage increased the representation of mothers who were Hispanic or non-White, younger, Medicaid recipients, or had low educational level. A total of 236,460 (92%; range by site, 82-100%) deliveries could be linked to a birth certificate.CONCLUSIONS:
Tailored approaches enabled linking most deliveries to infants and to birth certificates, even when data systems differed. The methods used may affect the composition of the population identified. Linkages established with such methods can support sound pharmacoepidemiology studies of maternal drug exposure outside the context of a formal registry.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Resultado da Gravidez
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Registro Médico Coordenado
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Bases de Dados Factuais
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Sistemas Computadorizados de Registros Médicos
/
Assistência Perinatal
Tipo de estudo:
Clinical_trials
/
Prognostic_studies
Limite:
Adolescent
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Adult
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Female
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Humans
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Newborn
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Pregnancy
País como assunto:
America do norte
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article