[New insight of genome-wide association study (GWAS)].
Nihon Rinsho
; 71(2): 231-6, 2013 Feb.
Article
em Ja
| MEDLINE
| ID: mdl-23631198
ABSTRACT
The number of obese patients is increasing in Japan, due to the westernization of lifestyle. Obesity, especially visceral fat obesity, is important for the development of metabolic syndrome. Genetic factors are important for the development of obesity as well as environmental factors. Importance of genetic factors of fat distribution is also reported. Recent genome-wide association studies (GWASs) have revealed the obesity and fat distribution-related polymorphisms. GWAS will highlight a better understanding of the underlying molecular mechanisms in the regulation of obesity and distribution of body fat.
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Base de dados:
MEDLINE
Assunto principal:
Polimorfismo Genético
/
Predisposição Genética para Doença
/
Estudo de Associação Genômica Ampla
/
Obesidade
Tipo de estudo:
Risk_factors_studies
Limite:
Humans
País como assunto:
Asia
Idioma:
Ja
Ano de publicação:
2013
Tipo de documento:
Article