Treatment of psychotic and behavioral symptoms with clozapine, aripiprazole, and reboxetine in a patient with Huntington's disease.
Int Clin Psychopharmacol
; 28(4): 214-6, 2013 Jul.
Article
em En
| MEDLINE
| ID: mdl-23652781
ABSTRACT
We report on the successful use of a combined psychopharmacological treatment in a patient with Huntington's disease, at age 39, suffering from severe psychotic and behavioral symptoms. He presented with a schizophreniform psychosis accompanied by aggressive behavior leading to admission to the locked ward of our hospital. After unsatisfactory control of the psychiatric symptoms with olanzapine, risperidone, and amisulpride, we introduced aripiprazole. This did not affect the psychotic symptoms; however, led to an improvement in aggressive behavior, motivation, and even chorea. Accordingly, we choose not to switch medication but to add clozapine. Nevertheless, his delusions improved slightly, and further add-on treatment with reboxetine brought a further beneficial effect on motivation and activities of daily living. As chorea was not disabling in our patient, tetrabenazine has not yet been tried. Treatment was safe without any relevant side effects.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Piperazinas
/
Transtornos Psicóticos
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Antipsicóticos
/
Morfolinas
/
Clozapina
/
Doença de Huntington
/
Quinolonas
/
Agressão
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Limite:
Adult
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Humans
/
Male
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article