Putting the pieces together: necrolytic migratory erythema and the glucagonoma syndrome.
J Gen Intern Med
; 28(11): 1525-9, 2013 Nov.
Article
em En
| MEDLINE
| ID: mdl-23681843
ABSTRACT
Glucagonomas are slow-growing, rare pancreatic neuroendocrine tumors. They may present with paraneoplastic phenomena known together as the "glucagonoma syndrome." A hallmark sign of this syndrome is a rash known as necrolytic migratory erythema (NME). In this paper, the authors describe a patient with NME and other features of the glucagonoma syndrome. The diagnosis of this rare tumor requires an elevated serum glucagon level and imaging confirming a pancreatic tumor. Surgical and medical treatment options are reviewed. When detected early, a glucagonoma is surgically curable. It is therefore imperative that clinicians recognize the glucagonoma syndrome in order to make an accurate diagnosis and refer for treatment.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Pancreáticas
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Eritema Migratório Necrolítico
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Glucagonoma
Limite:
Female
/
Humans
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Middle aged
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article