Chemical proteomics-driven discovery of oleocanthal as an Hsp90 inhibitor.
Chem Commun (Camb)
; 49(52): 5844-6, 2013 Jul 04.
Article
em En
| MEDLINE
| ID: mdl-23703283
ABSTRACT
Hsp90, a key target in cancer therapy, has been identified as the main partner of oleocanthal, an olive oil bioactive compound. A combination of chemical and biological assays disclosed its mechanism of action at the molecular level.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Fenóis
/
Proteínas de Choque Térmico HSP90
/
Proteômica
/
Aldeídos
Limite:
Humans
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article