Identification of canine parvovirus with the Q370R point mutation in the VP2 gene from a giant panda (Ailuropoda melanoleuca).
Virol J
; 10: 163, 2013 May 26.
Article
em En
| MEDLINE
| ID: mdl-23706032
ABSTRACT
BACKGROUND:
In this study, we sequenced and phylogenetic analyses of the VP2 genes from twelve canine parvovirus (CPV) strains obtained from eleven domestic dogs and a giant panda (Ailuropoda melanoleuca) in China. A novel canine parvovirus (CPV) was detected from the giant panda in China.RESULTS:
Nucleotide and phylogenetic analysis of the capsid protein VP2 gene classified the CPV as a new CPV-2a type. Substitution of Gln for Arg at the conserved 370 residue in CPV presents an unusual variation in the new CPV-2a amino acid sequence of the giant panda and is further evidence for the continuing evolution of the virus.CONCLUSIONS:
These findings extend the knowledge on CPV molecular epidemiology of particular relevance to wild carnivores.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ursidae
/
Proteínas Estruturais Virais
/
Parvovirus Canino
/
Mutação de Sentido Incorreto
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Animals
País como assunto:
Asia
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article