Molecular mechanism of peroxisome proliferator-activated receptor α activation by WY14643: a new mode of ligand recognition and receptor stabilization.
J Mol Biol
; 425(16): 2878-93, 2013 Aug 23.
Article
em En
| MEDLINE
| ID: mdl-23707408
Palavras-chave
AF-2; DBD; DMEM; DNA-binding domain; Dulbecco's modified Eagle's medium; HCEC; LBD; MD; PBS; PCA; PDB; PPAR; PPARα; Protein Data Bank; RMSF; activation function 2; crystal structure; dry eye disease; human corneal epithelial cells; ligand-binding domain; molecular dynamics; peroxisome proliferator-activated receptor; phosphate-buffered saline; principal component analysis; protein and ligand interaction; root-mean-square fluctuation
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Pirimidinas
/
PPAR alfa
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article