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Diabetes mellitus, hypertension and albuminuria in rural Zambia: a hospital-based survey.
Rasmussen, Jon B; Thomsen, Jakúp A; Rossing, Peter; Parkinson, Shelagh; Christensen, Dirk L; Bygbjerg, Ib C.
Afiliação
  • Rasmussen JB; Department of International Health, Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.
  • Thomsen JA; Department of International Health, Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.
  • Rossing P; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.
  • Parkinson S; Steno Diabetes Center, Gentofte, Denmark.
  • Christensen DL; Faculty of Health, Aarhus University, Aarhus, Denmark.
  • Bygbjerg IC; Dr. Gray's Hospital, Elgin, UK.
Trop Med Int Health ; 18(9): 1080-1084, 2013 Sep.
Article em En | MEDLINE | ID: mdl-23763632
ABSTRACT

OBJECTIVE:

To assess albuminuria in rural Zambia among patients with diabetes mellitus only (DM group), hypertension only (HTN group) and patients with combined DM and HTN (DM/HTN group).

METHODS:

A cross-sectional survey was conducted at St. Francis Hospital in the Eastern province of Zambia. Albumin-creatinine ratio in one urine sample was used to assess albuminuria. Other information obtained included age, sex, body mass index (BMI), waist circumference (WC), blood pressure (BP), glycosylated haemoglobin (HbA1c ), random capillary glucose, time since diagnosis, medication and family history of DM or HTN.

RESULTS:

A total of 193 participants were included (DM group n = 33; HTN group n = 92; DM/HTN group n = 68). The participants in the DM group used insulin more frequently as diabetes medication than the DM/HTN group (P < 0.05). Furthermore, the DM group was younger and had lower BMI, WC and BP than the two other groups. In the DM group, HTN group and DM/HTN group, microalbuminuria was found in 12.1%, 19.6% and 29.4% (P = 0.11), and macroalbuminuria was found in 0.0%, 3.3% and 13.2% (P = 0.014), respectively. The urine albumin (P = 0.014) and albumin-creatinine ratio (P = 0.0006) differed between the three groups.

CONCLUSION:

This hospital-based survey in rural Zambia found a lower frequency of albuminuria among the participants than in previous studies of patients with DM or HTN in urban sub-Saharan Africa.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Complicações do Diabetes / Diabetes Mellitus / Albuminúria / Hipertensão Tipo de estudo: Diagnostic_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Humans País como assunto: Africa Idioma: En Ano de publicação: 2013 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Complicações do Diabetes / Diabetes Mellitus / Albuminúria / Hipertensão Tipo de estudo: Diagnostic_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Humans País como assunto: Africa Idioma: En Ano de publicação: 2013 Tipo de documento: Article