Glutamine derivatives as novel anticancer agents acting via gastrin binding sites.
Med Hypotheses
; 32(2): 85-8, 1990 Jun.
Article
em En
| MEDLINE
| ID: mdl-2377092
ABSTRACT
With regard to the structural analogies between the C-terminal tetrapeptide of gastrin, gastrin receptor antagonists and anticancer derivatives of glutamine, it is plausible to propose that the mechanism of the anticancer activity may be related to interaction with the gastrin receptor. Dietary glutamine intake and glutamine metabolites may also influence the activity of gastrin receptors.
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Base de dados:
MEDLINE
Assunto principal:
Receptores da Colecistocinina
/
Glutamina
/
Antineoplásicos
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
1990
Tipo de documento:
Article