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E3 ubiquitin ligase Fbw7 negatively regulates granulocytic differentiation by targeting G-CSFR for degradation.
Lochab, Savita; Pal, Pooja; Kapoor, Isha; Kanaujiya, Jitendra Kumar; Sanyal, Sabyasachi; Behre, Gerhard; Trivedi, Arun Kumar.
Afiliação
  • Lochab S; Drug Target Discovery and Development Division, CSIR-Central Drug Research Institute (CSIR-CDRI), Sector-10, Jankipuram Extension, Lucknow, 226031 UP, India.
  • Pal P; Drug Target Discovery and Development Division, CSIR-Central Drug Research Institute (CSIR-CDRI), Sector-10, Jankipuram Extension, Lucknow, 226031 UP, India.
  • Kapoor I; Drug Target Discovery and Development Division, CSIR-Central Drug Research Institute (CSIR-CDRI), Sector-10, Jankipuram Extension, Lucknow, 226031 UP, India.
  • Kanaujiya JK; Drug Target Discovery and Development Division, CSIR-Central Drug Research Institute (CSIR-CDRI), Sector-10, Jankipuram Extension, Lucknow, 226031 UP, India.
  • Sanyal S; Drug Target Discovery and Development Division, CSIR-Central Drug Research Institute (CSIR-CDRI), Sector-10, Jankipuram Extension, Lucknow, 226031 UP, India.
  • Behre G; Division of Hematology and Oncology, University Hospital of Leipzig, Johannissallee 32A, 04103 Leipzig, Germany.
  • Trivedi AK; Drug Target Discovery and Development Division, CSIR-Central Drug Research Institute (CSIR-CDRI), Sector-10, Jankipuram Extension, Lucknow, 226031 UP, India. Electronic address: arun3vedi@yahoo.com.
Biochim Biophys Acta ; 1833(12): 2639-2652, 2013 Dec.
Article em En | MEDLINE | ID: mdl-23820376
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diferenciação Celular / Receptores de Fator Estimulador de Colônias de Granulócitos / Proteínas de Ciclo Celular / Ubiquitina-Proteína Ligases / Proteínas F-Box / Proteólise / Granulócitos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2013 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diferenciação Celular / Receptores de Fator Estimulador de Colônias de Granulócitos / Proteínas de Ciclo Celular / Ubiquitina-Proteína Ligases / Proteínas F-Box / Proteólise / Granulócitos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2013 Tipo de documento: Article