Molecular pathogenesis of hepatic adenomas and its implications for surgical management.
J Gastrointest Surg
; 17(10): 1869-82, 2013 Oct.
Article
em En
| MEDLINE
| ID: mdl-23835731
ABSTRACT
INTRODUCTION:
Hepatic adenomas (HAs) are benign tumors of the liver, which can be solitary or multiple, and have a definite risk of malignant degeneration.DISCUSSION:
The pathogenesis and natural history of this disease entity were previously unknown. Recent research into the molecular pathogenesis of this condition has provided evidence for the malignant transformation of some of these adenomas. In the current article, we discuss the current evidence on the molecular biology underlying malignant transformation of hepatic adenomas and the implications for the surgical management of this disease.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Adenoma
/
Neoplasias Hepáticas
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article